- Prioritise AP and ATK substats, flat PEN is also decent with Nicole's Def Shred.
- Alice has AM->AP conversion in her kit so 2p
Phaethon's Melody is more efficient on her than other Anomaly agents. You can consider other 2p options with good substats. 
Weeping Gemini is her best F2P option, and should outperform 
Fusion Compiler and 
Sharpened Stinger in Deadly Assault.
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Alice, Yuzuha, Nicole
Deadly Assault
Alice
Yuzuha
Nicole
4 Limited
3 Limited
Showcase Tabs
The Defiler (S20)
Miasmic Fiend (S17)
Video Showcase
The Defiler (S20)
Miasmic Fiend (S17)
Agent 1
The Defiler (S20)
Miasmic Fiend (S17)
AgentAlice
W-EnginePracticed Perfection
4-Pc Drive DiscFanged Metal
2-Pc Drive DiscPhaethon's Melody
Agent 1 Details
The Defiler (S20)
Miasmic Fiend (S17)
Alice M0W1
Main Stats | ||
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4 - Anomaly Proficiency | 5 - Physical DMG% | 6 - Anomaly Mastery% |
Substats (30) | ||||
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Agent 2
The Defiler (S20)
Miasmic Fiend (S17)
AgentYuzuha
W-EngineWeeping Cradle
4-Pc Drive DiscAstral Voice
2-Pc Drive DiscPhaethon's Melody
- Prioritise ATK% substats/mainstats to maximize the buff from
Core Passive: Whimsical Wonder (3000 ATK required). You can consider AP 4 after reaching this threshold. - Yuzuha's mindscapes (especially her M2 Full of Colorful Company) improve team Anomaly buildup and increase the overall ceiling of the team, allowing for faster rotations and better decibel gain.
Kaboom the Cannon or 
Weeping Cradle are good alternatives to her Signature Engine.
Agent 2 Details
The Defiler (S20)
Miasmic Fiend (S17)
Yuzuha M2W0
Main Stats | ||
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4 - ATK%/Anomaly Proficiency | 5 - ATK% | 6 - Anomaly Mastery% |
Substats | ||||
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Agent 3
The Defiler (S20)
Miasmic Fiend (S17)
AgentNicole
W-EngineKaboom the Cannon
4-Pc Drive DiscMoonlight Lullaby
2-Pc Drive DiscPhaethon's Melody
- Nicole is built as an Anomaly character - AM6, 2p Phaethon's Melody as well as AP and ATK% substats. This is especially potent when considering Yuzuha's buffs, the DA Buff and the Miasmic Fiend boss buff.
Swing Jazz has high uptime when combined with Yuzuha M2, but 
Freedom Blues can be used instead depending on team investment.- Kaboom the Cannon or
The Vault are both great Engine options, with Vault offering more Energy at the cost of less buff uptime.
Agent 3 Details
The Defiler (S20)
Miasmic Fiend (S17)
Nicole M6W5
Main Stats | ||
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4 - Anomaly Proficiency | 5 - Ether DMG% | 6 - Anomaly Mastery/Energy Regen% |
Substats | ||||
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Run Specific Notes
The Defiler (S20)
Miasmic Fiend (S17)
The Defiler
Season 20
HP: 99,020,956
Buff: Aberration
- Increases the Agent's Anomaly Buildup Rate by 20%.
- When inflicting Attribute Anomaly on enemies, all squad members gain 60 points of Anomaly Proficiency, and DMG caused by Disorder increases by 40% for 15 seconds.