Relics are powerful items that work in a similar fashion to Talismans, but are equipped before each run. Each relic comes in one of four different colors, and can only be slotted in a respective colored socket of a player character. They come in three different qualities - each providing different set of benefits.
NightreignRelics - Nightreign Wiki

Besmirched Frame
Relics
- Taking attacks improves attack power
- Faith +3

Black Claw Necklace
Relics
- Defeating enemies near Totem Stela restores HP
- Defeating enemies fills more of the Art gauge
- Poise +3

Blessed Flowers
Relics
- [Executor] While Character Skill is active, unlocking use of cursed sword restores HP
- Dexterity +3

Blessed Iron Coin
Relics
- [Duchess] Defeating enemies while Art is active ups attack power
- Continuous HP Recovery
- Vigor +3

Bone-Like Stone
Relics
- [Recluse] Activating Ultimate Art raises Max HP
- [Recluse] Suffer blood loss and increase attack power upon Art activation
- Intelligence +3

Cracked Sealing Wax
Relics
- [Ironeye] Extends duration of weak point
- Critical Hits Earn Runes

Cracked Witch's Brooch
Relics
- [Guardian] Slowly restores nearby allies' HP while Art is active
- [Guardian] Reflect a portion of damage received when ability is activated
- Vigor +3

Crown Medal
Relics
- [Duchess] Dagger chain attack reprises event upon enemies
- Improved Dagger Attack Power

Dark Night of The Baron
Relics
- Improved Critical Hits +1
- Improved Critical Hits
- Critical Hits Earn Runes

Dark Night of The Beast
Relics
- Stamina recovers with each successful attack +1
- Changes compatible armament's skill to Flaming Strike at start of expedition
- Fire Attack Power Up +1

Dark Night of The Champion
Relics
- Increased Maximum Stamina
- Boosts Attack Power of Added Affinity Attacks
- Defeating enemies fills more of the Art gauge

Dark Night of The Demon
Relics
- Taking attacks improves attack power

Dark Night of The Fathom
Relics
- Increased Maximum HP
- Slowly restore HP for self and nearby allies when HP is low
- Continuous HP Recovery: Slowly restores HP

Dark Night of The Miasma
Relics
- Nearby Frostbite Conceals Self
- Starting armament inflicts frost
- Improved Physical Damage Negation: Boosts physical damage negation

Dark Night of The Wise
Relics
- Increased Maximum FP
- Max FP permanently increased after releasing Sorcerer's Rise mechanism
- FP Restoration upon Successive Attacks: Successive attacks restore FP

Delicate Burning Scene
Relics
- Random Relic Effect

Delicate Drizzly Scene
Relics
- Random Relic Effect

Delicate Luminous Scene
Relics
- Random Relic Effect

Delicate Tranquil Scene
Relics
- Random Relic Effect

Edge of Order
Relics
- [Ironeye] Boosts thrusting counterattacks after executing Art
- Starting armament deals holy damage
- Improved Bow Attack Power

Fell Omen Fetish
Relics
- Switching Weapons Boosts Attack Power
- Improved Throwing Knife Damage
- Vigor +1

Golden Dew
Relics
- [Duchess] Improved Character Skill Attack Power
- Boosts Attack Power of Added Affinity Attacks

Golden Sprout
Relics
- [Executor] Roaring restores HP while Art is active
- HP Recovery From Successful Guarding
- Slowly restore HP for self and nearby allies when HP is low

Grand Burning Scene
Relics
- Random Relic Effect
- Random Relic Effect
- Random Relic Effect

Grand Drizzly Scene
Relics
- Random Relic Effect
- Random Relic Effect
- Random Relic Effect

Grand Luminous Scene
Relics
- Random Relic Effect
- Random Relic Effect
- Random Relic Effect

Grand Tranquil Scene
Relics
- Random Relic Effect
- Random Relic Effect
- Random Relic Effect

Night of the Baron
Relics
- Improved Critical Hits +1
- Art gauge fills moderately upon critical hit
- Critical Hit Boosts Stamina Recovery Speed

Night of the Beast
Relics
- Stamina recovers with each successful attack +1
- Starting armament deals fire damage

Night of the Champion
Relics
- Increased Maximum Stamina
- Guard counter is given a boost based on current HP
- HP Restoration upon Thrusting Counterattack

Night of the Demon
Relics
- Huge rune discount for shop purchases while on expedition
- Gesture "Crossed Legs" Builds Up Madness
- Madness Continually Recovers FP

Night of the Fathom
Relics
- Increased Maximum HP
- Flask Also Heals Allies
- Items confer effect to all nearby allies

Night of the Lord
Relics
- Switching Weapons Adds an Affinity Attack
- Boosts Attack Power of Added Affinity Attacks
- Switching Weapons Boosts Attack Power

Night of the Miasma
Relics
- Nearby Frostbite Conceals Self
- Changes compatible armament's skill to Chilling Mist at start of expedition
- Attack power up when facing frostbite-afflicted enemy

Night of the Wise
Relics
- Increased Maximum FP
- Starting armament inflicts poison
- Poison & Rot in Vicinity Increases Attack Power

Old Pocketwatch
Relics
- FP Restoration upon Successive Attacks
- Dexterity +3

Old Portrait
Relics
- [Revenant] Trigger ghostflame explosion during Ultimate Art activation
- [Revenant] Extend own HP to fully heal nearby allies when activating Art
- Defeating enemies fills more of the Art gauge

Polished Burning Scene
Relics
- Random Relic Effect
- Random Relic Effect

Polished Drizzly Scene
Relics
- Random Relic Effect
- Random Relic Effect

Polished Luminous Scene
Relics
- Random Relic Effect
- Random Relic Effect

Polished Tranquil Scene
Relics
- Random Relic Effect
- Random Relic Effect

Scenic Flatstone
Relics
- Purchasing this item randomly generates a random Delicate, Polished, or Grand relic.

Silver Tear
Relics
- [Wylder] Art gauge greatly filled when ability is activated
- Ultimate Art Gauge +3
- Arcane +3

Slate Whetstone
Relics
- [Wylder] Follow-up attacks possible when using Character Skill (greatsword only)
- Physical Attack Up

Small Makeup Brush
Relics
- [Revenant] Power up while fighting alongside family
- Increased rune acquisition for self and allies

Stone Stake
Relics
- [Guardian] Increased duration for Character Skill
- Character Skill Cooldown Reduction +3

The Wylder's Earring
Relics
- [Wylder] Art activation spreads fire in area
- [Wylder] +1 additional Character Skill use
- Stamina recovers with each successful attack

Third Volume
Relics
- [Guardian] Creates whirlwind when charging halberd attacks
- HP Restoration upon Halberd Attacks