Aatrox (1G) - Bastion

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Aatrox is a tank with the Bastion tag. His ability Stellar Slash heals him for (AP) health, then he deals (AD & Armor) physical damage to the current target.
With N.O.V.A. Strike Aatrox cleaves the battlefield, briefly knocking up all enemies and dealing (AD & Armor) physical damage.
Caitlyn (1G) - Fateweaver

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Caitlyn does not have a regular, active ability but instead it is the passive ability Aim for the Head. Her attacks have a chance of proccing lucy where she has the chance to fire an empowered headshot, dealing damage and (AD & AP) bonus physical damage.
With N.O.V.A Strike all enemies are marked, increasing damage taken. The first time marked targets drop below a threshold health, headshot them for (AD & AP) physical damage. With Fateweaver lucky active, check twice and take the better outcome.
Akali (2G) - Marauder

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Akali is a Marauder with the ability Star Strike. SHe respositions next to the target to strike the most enemies. She then throws Shurikens piercing Kunai, each dealing damage (AD) physical damage to the first enemy hit, reduced (AD) for subsequent targets. Kunai removes armor, increased if they crit.
N.O.V.A Strike she slices all enemies applying wound and bleed that deals damage per a second (AD) physical damage each second for the rest of combat. Kunai increases the damage of the bleed.
Maokai (3G) - Brawler

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Maokai is a brawler with the ability Grasp of Convergence which has an active and passive ability. The passive ability is Maokai gains more max health from all sources - making him a strong tank with the Brawler trait. For the active, coverage an X-shape of vines on the target, dealing (AP) magic damage to each enemy hit and stunning them.
For N.O.V.A Strike, send forth a wave of dragons that stun all enemies. For the rest of combat, Maokai’s attacks deal (health) bonus physical damage. Maokai's Grasp of Convergence abilities means that Warmogs and belt items will be a solid choice for him.
Kindred (4G) - Challenger

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Kindred has an active and passive ability with the name of Cosmic Pursuit. For the passive ability, attacks and abilities mark the target. When an enemy reaches a maximum number of marks, wolf consumes the marks, dealing (AD & AP) physical damage.
For the active, Kindred jumps up to a hex away and fires arrows at the nearest targets, each dealing spell (AD) physical damage. WIth N.O.V.A Strike, Kindred gains damage amp. Now and every second after Kindred adds a mark to all enemies.