Karthus·Mid Build

Most Popular

If you want to use the most popular Karthus Mid build, you should take Exhaust and Flash as your Summoner Spells. For runes, you should pick Dark Harvest as your keystone, followed by Cheap Shot, Eyeball Collection and Ultimate Hunter in the primary tree, as well as Presence of Mind and Coup de Grace in the secondary tree. For rune shards, you want Adaptive Force in offense, Adaptive Force in flex and Health Scaling in defense, though it depends on the matchup. Finally, for your items, you should build Malignance as your first item, followed by Sorcerer's Shoes and Liandry's Torment. For your last 3 items, you should build Shadowflame, Rabadon's Deathcap and finish with Void Staff. For the skill order, you want to stick with Q - E - W. Right now, this build has 50.5% winrate over 918 matches played.

Optional

Your second option for Karthus Mid build would be to take Flash and Teleport as your Summoner Spells. The runes that this build takes advantage of are First Strike as your keystone, Magical Footwear, Future's Market and Cosmic Insight in the primary tree, and Eyeball Collection with Ultimate Hunter in the secondary tree. The shards used in this build are Adaptive Force in offense, Adaptive Force in flex and Health Scaling in defense. The items for the build are Malignance, which you should build first, followed by Sorcerer's Shoes as your second item and Liandry's Torment as your third item. The rest of the items in order are Rabadon's Deathcap, Void Staff and Shadowflame. The skill order for this build is Q - E - W. In the current patch, this build has a 48.1% win rate over 399 matches.

Alternative

If you're looking for alternatives, you can use Flash and Teleport as your Summoner Spells, with runes being Dark Harvest as your keystone, Cheap Shot, Eyeball Collection and Ultimate Hunter in the primary tree, and Gathering Storm with Transcendence in the secondary tree, as well as Adaptive Force, Adaptive Force, and Health Scaling as your rune shards. The items that this build incorporates are Malignance as your first item, then Sorcerer's Shoes as a second item and Archangel's Staff as a third item. You want to finish the build with Liandry's Torment, Rabadon's Deathcap and Void Staff. As far as ability max order goes, you want to keep it Q - E - W. This build is currently sitting at a 46.1% win rate across 102 matches played.

Off-Meta

If you want to try an Off-Meta Karthus Mid build in the current patch, try Exhaust and Flash as your Summoner Spells, Dark Harvest, Cheap Shot, Eyeball Collection and Ultimate Hunter as your primary rune tree, and Presence of Mind with Last Stand as your secondary tree. Use Adaptive Force, Adaptive Force and Health Scaling as your shards. For items in this build, you want to complete Liandry's Torment as your first item, then finish Sorcerer's Shoes as your second item, and Malignance as third item. The last 3 options are Rabadon's Deathcap, Void Staff and Morellonomicon. The ability order for this build is Q - E - W. As of the current patch, this build has a 44.6% win rate over 74 matches played.

Situational Karthus Runes and Items

Depending on the context of your game, your matchup, and enemy champions, you might want to consider building some situational items or take specific runes. Carefully examine your team, enemy team, game state , and your matchup to plan your Karthus build accordingly! For example, when it comes to rune shards, you might want to take either Armor or Magic Resist, depending on which champion you are about to lane against.