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Karthus·Combos

Death DefiedP
Lay WasteQ
Wall of PainW
DefileE
RequiemR
Win rate50.5%
Pick rate3.3%
Ban rate5.1%
Matches5 550-
Karthus roleName has a 50.5% win rate and 3.3% pick rate in eloName and is currently ranked S tier. Below, you will find thorough guides with videos on every available Karthus combo. Learn, improve, and step up your Karthus gameplay with Mobalytics!
Lay Waste
Q
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Wall of Pain
W
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Defile
E
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Summoner FlashF
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Lay Waste
Q
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Lay Waste
Q

To engage Q W E as fast as you can and instantly Flash forward, followed by hitting Q as many times as you can.

Featured
Hard
Featured
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Lay Waste
Q
right arrow
Wall of Pain
W
right arrow
Defile
E
right arrow
fighting iconAA
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Lay Waste
Q
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Lay Waste
Q
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fighting iconAA

When at mid range Q W instantly followed by using E on your target. AA and right after use two Q's for every AA.

Average
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Lay Waste
Q
right arrow
Wall of Pain
W
right arrow
Lay Waste
Q
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Lay Waste
Q
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Requiem
R
right arrow
Lay Waste
Q

If you happen to die Q W instantly followed by two Q's. Use R quickly then one last Q as soon as the R channel finishes.

Average
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Lay Waste
Q
right arrow
Wall of Pain
W
right arrow
Requiem
R
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Summoner FlashF

If you're looking to deal damage as you retreat Q W instantly then R and F near the beginning of the cast animation.

Average
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Wall of Pain
W
right arrow
Lay Waste
Q
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Defile
E
right arrow
Lay Waste
Q
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Lay Waste
Q

When at long range W Q your target instantly then walk forward and E right before you are in range, then continue to use Q.

Easy
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Defile
E
right arrow
fighting iconAA
right arrow
Lay Waste
Q
right arrow
fighting iconAA
right arrow
Lay Waste
Q

When at close range E AA instantly followed by Q and using AA's in between every Q cast.

Easy
More info