Fiend, rotation target:
2 stun window with as high of disorder count as possible. Routing a rotation that make sure Alice doesn't get stonewalled by anomaly ICD is important.
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Alice Yuzuha Vivian
Deadly Assault
Alice
Yuzuha
Vivian
6 Limited
Showcase Tabs
DA S21
DA S18
Video Showcase
DA S21
DA S18
Agent 1
DA S21
DA S18
AgentAlice
W-EnginePracticed Perfection
4-Pc Drive DiscFanged Metal
2-Pc Drive DiscPhaethon's Melody
4pc 
Fanged Metal is Alice best in slot, and building as much AM with 2pc 
Phaethon's Melody and AM Disc 6 is the best build for her, both for high fight momentum with fast anomaly buildup, and considering she can convert her AM into AP.
PEN disc 5 becomes the best option for M0 Alice without Artful buff.
Agent 1 Details
DA S21
DA S18
Agent 1 M0W1
Main Stats | ||
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4 AP | 5 PEN / ATK / DMG | 6 AM |
Substats (34) | ||||
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Agent 2
DA S21
DA S18
AgentYuzuha
W-EngineMetanukimorphosis
4-Pc Drive DiscSwing Jazz
2-Pc Drive DiscPhaethon's Melody
Yuzuha alternative W-Engine would be 
Weeping Cradle or 
Kaboom the Cannon. Alternative W-Engine in this case specifically performs really well since 
Metanukimorphosis and aberration buff gives a similar buff.
You should use AP disc 4 on Yuzuha If you have enough ATK substats to get ~3000 ATK, as it minimize the physycal anomaly dilution caused by her own anomaly buildup.
Agent 2 Details
DA S21
DA S18
Agent 2 M0W1
Main Stats | ||
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4 AP / ATK | 5 ATK | 6 AM |
Substats (Count) | ||||
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Agent 3
DA S21
DA S18
AgentVivian
W-EngineFlight of Fancy
4-Pc Drive DiscPhaethon's Melody
2-Pc Drive DiscFreedom Blues
More than 50% of the damage is done by Vivian anomaly damage (Corruption, ether disorders, and abloom). So her having as high AP as possible is preferable. I find that AP substats for her weight twice more valuable for her than ATK%.
Flight of Fancy is needed in this rotation, without the 40% buildup buff, corruption proc might lagged behind and far slower since Typhon is neutral weakness. Without it, compensating the anomaly buildup with M2 Yuzuha or M2 Vivian is needed.
Agent 3 Details
DA S21
DA S18
Agent 3 M0W1
Main Stats | ||
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4 AP | 5 DMG / ATK | 6 AM |
Substats (30) | ||||
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Run Specific Notes
DA S21
DA S18
Miasmic Fiend - Unfathomable
Season 21
HP: 121503901
Buff:
Aberration
· Increases the Agent's Anomaly Buildup Rate by 20%.
· When inflicting Attribute Anomaly on enemies, all squad members gain 60 points of Anomaly Proficiency, and DMG caused by Disorder increases by 40% for 15 seconds.
How to Play & Additional Tips
the best way to getting high score against typhon is by utilizing its boss mechanics, making sure the fight phases advance as quickly as possible to get 4 impaired stun windows. Our target on each stun window is to get at least 5-6 disorder count, with assault, polarized assault, and corruption.
You also want to aim a strong rotation of Alice polarized assault by her hold basic as follows:
Assault > 
Alice hold basic > 
Vivian corruption > Polarized assault hits corruption for instant disorder
this interaction is what makes it possible for the team to fit up to 6 disorders inside each stun window
Another factor in damage optimization in the team is Vivian abloom count. Making sure there are no overflow Vivian feather when she uses her ultimate is the best case scenario, although it would be hard to do in this team since both Alice and 
Yuzuha has a moderate EX special energy cost.
Because this is a no stunner team, there will be enough time for only 4 stun window total (4800 performance point). To get a max performance point with only 4 stun window, some planning and quick play to get the fight advanced fast is needed for the last +200 performance with an extra defensive assist.