You just need 3-star Rengar + 3-star Kha'Zix + ANY 3-star tank champion (default Hecarim).
All the others are optional, flexible and not necessary.
Itemization:
Itemize Rengar first, since Kha'Zix needs time to evolve, so Kha'Zix is weak in the early game.
For Rengar
Rengar's one core and best item is Titan's Resolve. Since Rengar has both AD and AP ratios, Titan's Resolve provides everything he needs while also making him immune to CC once fully stacked.
Rengar core items:Guinsoo's Rageblade + Edge of Night + Titan's Resolve
Rengar is SUPER good with Ravager's Emblem, this is the best you can get on him.
Kha'Zix core items: Hand of Justice + Edge of Night + Rabadon's Deathcap Remember Kha'Zix should evolve Ravager first, so he can pair with Diana for 2 Ravagers. Then it's Rapidfire or Executioner, depends on your build.
Kha'Zix is picky with items, he really wants Artifacts rather than normal items. If you really don't have artifacts, you can just go Hand of Justice + Edge of Night as his core. His third item can be very flexible. Jeweled Gauntlet + Hand of Justice is also very decent.
Evenshroud for armor penetration, Sunfire Cape for burn/wound.
Gargoyle Stoneplate is good since you are focusing on one 3 stars tank champion.
When to Roll/How to Roll
Roll at Lv7 mainly, since you are playing 3 costs reroll. This gives the best chance to 3 star them.
However, you need to be strong early game for the stacks of Rengar and Kha'Zix, so don't be too greedy of econ. Level up and roll if it's necessary. You can also use this chance to buy extra wisp if it's a good one.
You can roll a little bit every round even before Lv7 if you already have pairs. You don't have to win every round, just need to kill enough enemies for the stacks. But win-streaking gives more gold and preserve your HP. And you really don't need to go Lv8 and Lv9 for this comp. So again don't save too much gold.
Alternate version
When you have "Double Trouble" augment at 3-2, you can play an extremely OP variation.
in this varation, every Rengar will gain double the amount of Mana from Kha'Zix. Every Kha'Zix will gain double the amount of HP recovery from Rengar. And you also have stronger basic stats.
This version also shows us that,the main tank can be any other 3-cost 3-star tank. Such as the Krug (Riftbeast Brawler) we are showing in this builder (but it's not usual) and potentially Rammus (Sprykin Defender) Fiddlestick (Flora Fatalia Defender) even Vi (Primal Juggernaut) as well.
Example of potentially other 3 stars you can chase at Lv7.
If there are a lot of Elderwood players in your lobby, it will be hard to 3-star Hecarim.
Scout the lobby to see which 3-cost tank champion is least contested. And also adjust it base on your shop, be flexible.