Slay the Spire 2 Card Tier List

Updated on Mar 12, 2026

Mar 12, 2026

Overview

Welcome to our preliminary Card tier list for Slay the Spire 2. Here we'll give you our rankings of the card pool for each of the five Characters.

While it's far from perfect, our intention is to help players better evaluate their picks during a run. Please be sure to read through our methodology, as the rankings alone won't determine a card's strength.

Disclaimer:

Seeing as the game has recently launched into Early Access, consider this an early look while we still learn and explore the mechanics of the game. We'll continue updating the list along the way, especially as future balance patches shake things up.

1. Overview 2. Methodology 3. Ironclad Tier List 4. Silent Tier List 5. Regent Tier List 6. Necrobinder Tier List 7. Defect Tier List

Methodology

Here's a quick look at how we'll be evaluating and ranking each card. By nature, each run of Slay the Spire is extremely contextual. Certain cards will be outstanding in some cases, yet completely useless in others. As such, the more flexible a card is, the higher we'll rate it.

Note: We won't be including Multiplayer cards here, but feel free to try them out during co-op!

S-Tier: The best of the best. These cards are highly sought after regardless of the archetype you're playing, and can generally be picked up at any time.

A-Tier: Cards in this tier are very cost-efficient, or they provide a strong and unique effect. Only a slight step down from S-Tier, as they may require some synergy.

B-Tier: The bread and butter pickups that make up a good portion of each deck. While not the cream of the crop, they're flexible and easy to splash anywhere.

C-Tier: These range from early game role-players to archetype-defining bombs. You'll generally want these to help solve early problems, or to top off synergies.

D-Tier: Highly situational or below the average rate. Either they require a specific draw order to work, or they're easy to use but have a relatively low impact.