[0.4] Gas Grenade Pathfinder - Simulacrum 3 Farmer

Overview:

Standard Pathfinder Poison-stacking setup utilising Gas Grenade & Plaguefinger.

Content: Great at farming Simulacrum, Ritual, Overrun Abyss Maps & Pinnacle Bosses where you can pre-stack clouds to fish for high damage/crit.

Mechanics Overview

Gas Grenade creates Poison Clouds, area ground surfaces that constantly apply Poison to Monsters within and grow in area over time. When combined with Herald of Plague, this build is easily able to clear large packs of Monsters. The Pathfinder's Overwhelming Toxicity doubles the amount of Poison stacks, helping to solve single target Damage.

Main Combo

The playstyle is very straightforward, just drop Gas Grenade to apply proliferating Poison to Monsters. Against tanky targets, use Despair followed by Toxic Domain, then stack Gas Grenade Poison Clouds on the mob.

Supporting Skills & Defences

Herald of Plague is used to provide Poison proliferation, allowing for smoother map clear. Despair will lower Monster Chaos Resistance, making them take more Chaos Damage from Poison. Withering Presence applies Wither to nearby Monsters, making them take increased Chaos Damage. Toxic Domain provides an additional single-target damage boost. On single target/bosses, you can also place down Dark Effigy to inflict extra stacks of Critical Weakness.

This build invests into both Evasion and Energy Shield, making use of Wind Dancer and Ghost Dance for a fairly stock-standard defensive setup for a build on the right-hand side of the Passive Skill Tree.

Ascendancy Progression:

Overwhelming Toxicity > Path Seeker > Relentless Pursuit > Running Assault

Campaign Quest Bonus Choices

• Act 2 Ancient Vows Quest: 30% increased Charm Charges gained
• Act 3 Corpse-snake Venom: 25% increased Stun Threshold
• Act 4 Blank Tattoos: +5 Dexterity, +5 Strength, +5 Intelligence
• Act 4 Goddess of Justice: 30% increased Life Recovery from Flasks
• Interlude Seven Pillars: +5% to Elemental Resistances or +5 to all Attributes (replace with 3% increased Movement Speed when Resistances/Attributes are solved in late game)

Videos:

Build Showcase:

• Simulacrum 3
• Xesht 3
• Arbiter of Ash

Build Updates(0.3):

• Day 1 Update
• Day 2 Update
• Day 3 Update (post)
• Discovery of Crit
• Day 4 Update (post)
• Day 5 Update
• Final Update
• Full Video Guide

See FAQ below for more information.

Q: Why Gas Grenade over Gas Arrow?

A: Gas Grenade has much higher effective damage for inflicted poisons (almost 3x).

Q: My chance to hit is low, why no accuracy scaling?

A: Gas Grenade's Poison Cloud bypasses the chance to hit calculation, it does not need Accuracy.

Q: Why no Escalating Poisons Support for extra poison stacks?

A: The support makes it harder to maintain maximum Poison stacks, and scaling damage for the existing stacks is more comfortable. We do utilise the support in our Toxic Domain link for single target.

Q: Does Crit actually work on Gas Grenade's Poison Cloud?

A: Yes, as of 0.3 it does.

• 28/08/25 - First draft
• 29/08/25 - Build posted
• 30/08/25 - Updated for new tree & support gems
• 31/08/25 - Updated endgame tree pathing(no longer taking Spectral Ward), updated gems
• 01/09/25 - Added new 3rd Ascension section, updated endgame gear, added Toxic Domain
• 02/09/25 - Added new Endgame Crit variant, updated gems (Arakaali's Lust)
• 07/09/25 - Updated for final changes & tweaks to gems, gear etc.
• 12/09/25 - Updated sections to consolidate Endgame crit and non-crit versions into a single version with crit splash (my current setup)
• 07/12/25 - Updated for 0.4 changes (see top of guide)
• 26/02/26 - Guide cleanup for end of 0.4