For a combo that gives a low chance of escape W and instantly Flash, then quickly Q E eAA followed by R to execute.
To quickly burst a low target Q. Once you confirm it will land use W and Flash instantly, then R.
When trying to engage on your target post level 6 Q and walk into E range to AA then W AA, execute with R.
If you're trying to all in a target with mobility or movement spells up W Q instantly then AA E and use R to execute.
For a decent melee trade W then quickly AA and instantly E after it completes to reset your AA. Q after your E slow connects then AA twice more.
To trade with your opponent at short range Q then instantly AA E. W as soon as your E connects then AA twice.