In this build primary focus should be getting Plasma to boost attack speed. This will stack onto the Thanatos buff the weapon already gives towards attack speed (granted you don't get hit).
Secondary focus should be Lifesteal/Healing; this can come from either Ares using Blood Spree or Apollo's Self Healing. I prefer Apollo's healing but aiming for both would be ideal. From there I recommend selecting boons that buff Omega Attack, Attack, and Sprint. Dodge would also be ideal.
In the arcana, you may ask... why put Strength if I'm putting Death? This is for security measures. I find it better because it gives a higher chance to beat the last boss once getting to them since I typically don't lose a defiance beforehand, even with Vows. Strength gives such a huge boost I find it worth to hold onto, even if inactive. However, if you wish to change it, I recommend replacing it with Night for Crit boost, or Huntress for more damage.
This build isn't strict and can be altered for the sake of what works for you. This is just what works for me.
































































