Exfoliatrix is a 
Jakobs Armor Shield.
Its special effect is Exfoliatrix - On Segment Break, gain increased Status Effect Chance for 6 seconds. Whenever enemies receive Status Effect Damage, recover a small portion of Shield.
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How to Unlock The Legendary Exfoliatrix Shield
Legendary Loot
Shields
Overview
How To Unlock
Unlock Location:
- Progress through the FL4K and the Last Resort DLC until reaching the Boss Cosmicreep or Gutslinger in a Digi-Rift (World Event).
Farm Method:
- Defeat Cosmicreep to get a chance at the Exfoliatrix.
- After use the Encore Machine nearby to reset the fight.
- Repeatedly defeat Cosmicreep until the Exfoliatrix drops.