Use your favourite features in-game with our Desktop App

Borderlands 4 Build

(Outrdated) Vex Infinite Bleed DPS Endgame

Vex

End Game

By NickTew

Updated on Oct 25, 2025

Oct 25, 2025

Build Overview

Bloodletter is absolutely disgusting in endgame, and likely bugged in various ways. Once you get a throwing knife with the Penetrator Augment making all sources of damage critically hit, your Bloodletter damage can crit, therefore re-proccing itself in an infinite loop. From what I can tell this is much more consistent with the Contamination Spec tree node, giving you extra status effect chance, so make sure you're getting this ASAP. Due to this interaction you can use literally any gun in the game to eventually do infinite damage. As a result, the skill tree has a lot of variation based on preference, and you can even use any action skill you want. I personally think Dead Ringer is the best for consistency, as while you're running through the game Incarnate is impossible to keep up 100% of the time unless you are in combat. The Spectres also feel great to use, but I'll have skill tree variations for each action skill listed below.

Check out my overall favorite build for Vex, the Blood Shot endgame build here which uses 0 bugs!

Leveling Build

Strengths And Weaknesses

Literal infinite damage
Can use any gun
Very Fun

Infinite Bleed is technically a bug, if you want a non-bugged build click here

Build Variants

Specter

Incarnate - Shotgun

Incarnate - SMG

Incarnate requires Grave Sustenance in order to keep it up, while it is quite fun to use and has a bit more survivabilty due to Energy Vampire I greatly prefer Dead Ringer because the Specters are consistent, do good damage, and I'm not reliant on my action skill what-so-ever.

Skill Tree

Specter

Incarnate - Shotgun

Incarnate - SMG

Points Spent 0 / 49

LMB Allocate

RMB Unallocate

5/5

3/3

5/5

3/3

You can realistically do whatever you want with your last like 10ish points - still testing lots of stuff

Initially I figured Mortal Terror would be very good with this setup however Bloodletter doesn't seem to be able to proc it so it doesn't help with our kill skill uptime too much, so you'd likely rather put the points elsewhere. Feel free to put the last 10 pts into it if you prefer though.

Gear to look out for

Penetrator Augment which comes on Throwing Knives is EXTREMELY powerful, and enables Bloodletter to stack on itself

Damage Amp Payload is also potent on Throwing Knives

Guns: Due to the kinetic synergies, almost any kinetic gun should work well. Ideally a high base damage shotgun. Shotguns pair very well with Penetrator Augment + Bloodletter Shotguns also generally have very high base damage which is important for Bloodletter scaling.

Underbarrel Attachments: Spread Launcher, Knife Launcher, and Shotgun. These have internal cooldowns, you can bypass the cooldown by swapping to a different gun with the same attachment.

Repkits: 200% Amp damage (good for shotguns or snipers) 100% action skill cooldown rate, Lifesteal, & Movement Speed are likely the best options for smooth leveling.

Equipment

Specter

Incarnate - Shotgun

Incarnate - SMG

Weapons

Repkits & Ordnance

Utilities

Gear to look out for

Penetrator Augment which comes on Throwing Knives is EXTREMELY powerful, and enables Bloodletter to stack on itself

Guns: Due to the kinetic synergies, almost any kinetic gun should work well. Ideally a high base damage Jakobs shotgun. Shotguns pair very well with Penetrator Augment + Bloodletter and are overall very strong weapons. Vladof SMGs especially the 'boory' type with a Jakobs ricochet barrel are very strong as well.

The Hot Slugger is my personal favorite gun, check out the written guide here:

Underbarrel Attachments: Spread Launcher, Knife Launcher, and Shotgun. These have internal cooldowns, you can bypass the cooldown by swapping to a different gun with the same attachment.

Repkits: 200% Amp damage (good for shotguns or snipers) 100% action skill cooldown rate

Class mod: Look for points in Bloodletter Material Components or Grave Implements, good stats include: Gun Damage, Shotgun/SMG Damage, Kinetic Damage, Status Damage, Movement Speed, Damage Reduction, Damage Dealt.

Enhancements: Jakobs 2x ricochet or stacking damage buff is good if using Hot Slugger, or use any Vladof enhancement if using a purple smg. Stats that are good: Crit damage, Gun damage, Gun specific crit damage, SMG fire rate, SMG mag size.