4pc 
Fanged Metal is Alice best in slot, and building as much AM with 2pc 
Phaethon's Melody and AM Disc 6 is the best build for her, both for high fight momentum with fast anomaly buildup, and considering she can convert her AM into AP.
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Alice Yuzuha Yanagi
Deadly Assault
6 Limited
Alice
Yuzuha
Yanagi
Showcase Tabs
DA S18
Shiyu S30
Video Showcase
DA S18
Shiyu S30
Agent 1
DA S18
Shiyu S30
AgentAlice
W-EnginePracticed Perfection
4-Pc Drive DiscFanged Metal
2-Pc Drive DiscPhaethon's Melody
Agent 1 Details
DA S18
Shiyu S30
Agent 1 M0W1
Main Stats | ||
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4 AP | 5 PEN / ATK / DMG | 6 AM |
Substats (32) | ||||
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Skill Levels | ||
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Agent 2
DA S18
Shiyu S30
AgentYuzuha
W-EngineMetanukimorphosis
4-Pc Drive DiscSwing Jazz
2-Pc Drive DiscPhaethon's Melody
Yuzuha alternative W-Engine would be 
Weeping Cradle or 
Kaboom the Cannon, but the damage difference is quite high between her signature, since the AP boost matters a lot for both Alice and Yanagi.
You should use AP disc 4 on Yuzuha If you have enough ATK substats to get ~3000 ATK, as it minimize the physycal anomaly dilution caused by her own anomaly buildup.
In the video, Yuzuha still use 4pc 
Swing Jazz, but the upcoming 4pc Moonlight Lullaby is a better upgrade for her buff uptime and amount.
Agent 2 Details
DA S18
Shiyu S30
Agent 2 M0W1
Main Stats | ||
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4 AP / ATK | 5 ATK | 6 AM |
Substats (Count) | ||||
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Skill Levels | ||
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Agent 3
DA S18
Shiyu S30
AgentYanagi
W-EngineTimeweaver
4-Pc Drive DiscChaos Jazz
2-Pc Drive DiscFreedom Blues
High AP build. AM disc 6 to get fast anomaly proc inside the limited stun window time. stacking PEN ratio with PEN disc 5.
Agent 3 Details
DA S18
Shiyu S30
Agent 3 M0W1
Main Stats | ||
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4 AP | 5 PEN / DMG / ATK | 6 AM |
Substats (26) | ||||
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Run Specific Notes
DA S18
Shiyu S30
Autonomous Assault Unit - Typhon Destroyer
Season 18
HP: 89614299
Buff:
Power Boost.
· For Agents, Electric DMG and Physical DMG increase by 30%.
· When inflicting Attribute Anomaly on enemies, for the whole squad, ATK increases by 8% and Decibel Generation Rate increases by 8% for 20s, stacking up to 4 times. Repeated triggers reset the duration
How to Play & Additional Tips
the best way to getting high score against typhon is by utilizing its boss mechanics, making sure the fight phases advance as quickly as possible to get 4 impaired stun windows. Our target on each stun window is to get at least 5-6 disorder count, with assault, polarized assault, and shock.
You also want to aim a strong rotation of Alice polarized assault by her hold basic as follows:
this interaction is what makes it possible for the team to fit up to 6 disorders inside each stun window. target to fit 2 electric disorder by Yanagi inside each stun window, and better yet if all of it is instantly procced by Alice polarized assault, as Yanagi is a higher damage dealer in this team scenario.
The team has a really good matchup against Typhon specifically, making a 3 stun window kill with about 2:10 time possible, but we can use the remaining time for performance point farming to get max score instead. Because this is a no stunner team, there will be enough time for only 4 stun window total (4800 performance point). To get a max performance point with only 4 stun window, some planning and quick play to get the fight advanced fast is needed for the last +200 performance with an extra defensive assist.