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PoE 2 Build

Poison Concoction End Game Build

presentationRanger
presentationPathfinder
End Game
Creator
0.1 Early Access
Updated on Jun 23, 2025
Jun 23, 2025

Build Overview

Concoction End Game Build

This is a build that you can do in a budget to reach not just end game but also +4 difficulty in every end game content.

This build gives high survivability and it's easy to play after all 90% of the time you just need 1 skill.

As the name says this is a build based in Poisonous Concoction and we aim to do a lot of chaos damage that amplify the poison damage. Besides this we are using a couple of tricks that I will talk about and explain everything in this Guide.

Build Variants

This build is all about Poisonous Concoction most of your damage will came from this skill and we will use a couple of tricks to increase this damage. Like Eye of Winter with the right support gems that will increase our damage.

To create a similar build you need at least 196 spirit that you can get from amulet and chest but you can do this build with less than this.

Another requirement is the Widowhail together with a good quiver will increase our damage by a lot!

The last piece of item that is not mandatory but will increase your damage is the Hand of Wisdom and Action.

A good mana flask and belt is also really important to make this build work in every situation.

Bellow I will explain everything in detail that you need to know.

Equipment

item
2
item
4
item
1
item
7
item
6
item
5
item
3
item
8
item
9
item
10
item
item
item
item
item
Equipment Priority
0
Helmet
Expert Feathered Tiara
1
Main Hand
Widowhail
2
Off Hand
Two-Point Quiver
3
Left Ring
Gold Ring
4
Right Ring
Ring
5
Amulet
Gold Amulet
6
Body
Advanced Scalper's Jacket
7
Gloves
Hand of Wisdom and Action
8
Belt
Rawhide Belt
9
Boots
Expert Threaded Shoes

EQUIPMENT

For this build you will need some good stuff but not expensive as you may think. You will need at least 196 spirit to get every buff I am using and equipment with the right stats!

WEAPON

The weapon is pretty straight forward all you need to find is a Widowhail ideally with 280% increased bonuses gained from quiver offcorse if you can't afford for this one because the higher the number more expensive it is start with one lower, for example the one I have at the moment is just 268%.

QUIVER

Since we are using Widowhail quiver is super important the best quiver you can use is a Visceral Quiver since Critical Strike will scale our chaos and poison damage. +2 To level of all projectile skills is a mandatory modifier, since with Winged Spear will multiply this number and increase a lot your Poisonous Concoction and since it will not increase it cost it will only increase our damage.
List of stats by prioritization:
- +2 To Level Of All Projectile Skills
- % Increased Critical Hit Chance For Attacks
- % Increased Critical Damage Bonus For Attack Damage
- % Increased Attack Speed
- adds # to # Fire/cold/ physical damage to attacks
- Projectile Speed

HELMET

Helmet will be our main source of energy shield being our second only layer of protection since we are using Chaos Inoculation we want a decent shield. Besides this Subterfuge Mask will also help to increase our evasion as well.
List of stats by prioritization:
- % Increased Energy Shield
- +# To Maximum Energy Shield
- Resistances that you may need
- Dexterity or Intelligence
- % Increased Rarity Of Items Found

BODY ARMOUR

This will be one of our sources for spirit and also layers of defence. You want to look for a body armour with full evasion ideally but one with evasion + energy shield can work as well. Since we are using Spectral Ward the evasion rating will be converter to energy shield.
List of stats by prioritization:
- +# To Spirit
- +# To Evasion Rating
- % Increased Evasion
- Resistances you may need
- Intelligence or Dexterity
- % Increased Rarity Of Items Found

BOOTS

Boots are all about movement speed specially for this build. We want to get ones with as much movement speed as possible, 30% minimum. On this equipment we are using evasion and energy shield main stats.
List of stats by prioritization:
- % Increased Movement Speed
- % Increased Evasion And Energy Shield
- Resistances you may need
- % Increased Rarity Of Items Found
- +# To Maximum Mana

BELT

This is a super important item we use mana flasks as our main resource to attack and a good belt will help with that, thanks to modifiers that will reduce the number of flasks charges used.
List of stats by prioritization:
- % Reduced Flask Charges Used (mandatory)
- Any resistances you may need
- + # To Maximum Mana
- % Increased Rarity Of Items Found

WEAPON

In this build we are using Hand of Wisdom and Action but you can use regular gloves as well. This unique gloves will help to increase our damage and attack speed as well and this will be the best gloves you can choose but if you don't have ones right now this are the stats you should look for.
List of stats by prioritization:
(Evasion Rating Gloves)
- Adds # To # Fire/ Cold Or Physical Damage to Attacks
- Any Resistances you may need
- Dexterity or Intelligence
- + # To Maximum Mana
- % Increased Rarity Of Items Found

RINGS

Rings are really important since this will be one of the items where you can get more Chaos Damage if you find the right rings for you!
List of stats by prioritization:
- % Increased Chaos Damage
- Ads # To # Physical Damage To Attacks
- Any Resistance you may need
- Dexterity Or Intelligence
- # To Evasion Rating
- Any lightning, fire or cold damage (scales with the damage gained as chaos)
- % Increased Rarity Of Items Found

AMULET

There are several good amulet you can use like Gold Amulet to increase Rarity, Stellar Amulet to increase attributes or Solar Amulet for more spirit, and we really need spirit for this build.
Besides this, amulet will be another item we can get more energy shield.

List of stats by prioritization:
- # To Spirit ( ideally you want at least 50 spirit here)
- % Increased Maximum Energy Shield
- + # To Maximum Energy Shield
- # To Level Of Projectile Skills
- +# To All Attributes
- Dexterity or Intelligence
- Any Resistances You May Need
- % Increased Rarity Of Items Found

The best instil you can pick with this build is Spaghettification will increase our chaos damage, attributes and movement speed.

FLASKS

Flasks are really important for this build. Life flask can be any that gives you a good amount of life but for the Mana Flasks there is a modifier that you really want to look for, %Increased Charges is super useful for this build since we use charges from this having more we can cast Poisonous Concoction as much we want without worrying about spending all of them.

RUNES

  • Weapon: For Widowhail we really want to get some Soul Core of Ticaba to increase our critical damage bonus.
  • Helmet you can go with Iron Rune or resistances runes if you need.
  • Body armour go with Iron Rune to scale evasion and energy shield.
  • Boots you can choose between Iron Rune or any resistances runes to cap your resistances.
  • Gloves you can slot any Resistances runes you may need.

CHARMS

Thawing Charm never fails to prevent that horrible freeze.

JEWELS

jewels are a strong component in this build.
You really need a Controlled Metamorphosis to get those 5 nodes without having to really connect the path and this way we can afford some extra nodes to make this build stronger.

Overall Emerald is the way to and get a few with a stats bellow.
List of stats by prioritization:
- % Increased bonuses Gained From Equipped Quiver
- % Increased Critical Hit Chance For Attacks
- % Increased Magnitude of poison you inflict
- % Increased Critical Damage Bonus
- Projectile Damage
- Attack Speed
- Evasion Rating

Skill Gems

Support Gem Requirements:

Str 10

Dex 40

Int 40

Expand all
1

Poisonous Concoction

Poisonous Concoction
supportmultipleprojectilesplayer
supportfasterattackplayer
supportaddedchaosdamageplayer
supportchaosmasteryplayer
supportburstingplagueplayer
2

Eye of Winter

Eye of Winter
supportunleashplayer
supportextractionplayer
supportwitheringtouchplayer
supportchancetopoisonplayer
3

Withering Presence

Withering Presence
4

Blasphemy

Blasphemy
despairplayer
supportcurseeffectplayer
supportdecayinghexplayer
supportincreasedareaofeffectplayer
5

Grim Feast

Grim Feast
6

Wind Dancer

Wind Dancer
supportclosecombatplayer
supportmaimplayer
supportblindplayer
7

Ghost Dance

Ghost Dance
8

Vine Arrow

Vine Arrow
supportragefountainplayer
supportdeadlypoisonplayer
moredurationsupportplayer
Gem Priority
+19

SKILL GEMS

Most of the time you only need to use Poisonous Concoction.
This is the main skill for this build and you need most of the time, this support gems will increase our damage. Scattershot will show as it decreased your dps but in reality will be much higher since we are shooting 2 additional projectiles the damage you see is multiplied by 3.

Eye of Winter use a skill gem level 13 is the minimum you can use. Since we will have a really high level for projectile this skill will be very expensive but we only need to use it against bosses and just once in a while. With this skill we don't care about damage but what we are really looking for is the effect from the slotted gems. Unleash will help to shoot 2 of these skills and this way with Withering Touch you will apply withered much faster. Withered will increase your chaos damage overall.

Next we have Vine Arrow to be honest you don't really need to use it but if you want this ability is only against bosses. Thanks to Font of Rage this flower created by this skill will give you up to 30 rage equal to 30% increased damage.

SPIRIT GEMS

As you guys can see we have a lot of spirit gems and they will make our damage and map clearing easier.
As defensive we have Grim Feast since we will be increasing intellect you can get the higher level as possible and this will give you extra energy shield and with this you can double the amount of energy shield you are using. Wind Dancer will increase your evasion rating and if you increase the quality it will help as well. Every time the enemies hit you they will be knocked back. And if they hit you we have Ghost Dance that will grant you a % of energy shield according with your evasion rating.

Then we have 2 spirit gems that will help to increase our damage. Withering Presence will increase the amount of chaos damage on enemies and Blasphemy will make our life easier. Thanks to this one you can slot Despair and this curse will be applied to every enemy that will came close to you. Decaying Hex will help to increase a little bit more you r damage.

Passive Tree

main:
123
123
set 1:
20
20
set 2:
20
20

On this build we want to get as much poison and chaos damage as possible.

Magnitude will increase the amount of damage poison does and duration will increase the duration. But since we can spam Poisonous Concoction as much we want Magnitude will be much better.

Master Fletching will help to increase even more the bonuses from our quiver.

Subterfuge Mask will help to increase our evasion rating using a helmet full of energy shield while Spectral Ward will give us more energy shield if using a body armour full of evasion rating.

This build we are also using Chaos Inoculation and this way we are immune to chaos damage and Eternal Youth as well, this way we can recover energy shield with flasks.

As you can see we are looking for a lot of critical strike and critical damage bonus since these can scale much more our damage.

To get all of this node you will need a Controlled Metamorphosis with a medium-large ring this way you can slot 7 nodes that will improve this build a lot without having to connect them and this way we can spend this passive points somewhere else.

How it Plays

Map Clearing: Poisonous Concoction all the way

Boss: Eye of Winter to apply withering then spam Poisonous Concoction. When you notice the withering stacks are lowering use again Eye of Winter and spam Poisonous Concoction once again.
If you want, you can use Vine Arrow with Font of Rage to increase your damage for a little bit but it's not mandatory.

Video Guide

Table of Contents

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