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Borderlands 4 Build

(Outrdated) Vex Infinite Bleed DPS Endgame

Vex

End Game

By NickTew

Updated on Oct 25, 2025

Oct 25, 2025

Build Overview

Bloodletter is absolutely disgusting in endgame, and likely bugged in various ways. Once you get a throwing knife with the Penetrator Augment making all sources of damage critically hit, your Bloodletter damage can crit, therefore re-proccing itself in an infinite loop. From what I can tell this is much more consistent with the Contamination Spec tree node, giving you extra status effect chance, so make sure you're getting this ASAP. Due to this interaction you can use literally any gun in the game to eventually do infinite damage. As a result, the skill tree has a lot of variation based on preference, and you can even use any action skill you want. I personally think Dead Ringer is the best for consistency, as while you're running through the game Incarnate is impossible to keep up 100% of the time unless you are in combat. The Spectres also feel great to use, but I'll have skill tree variations for each action skill listed below.

Check out my overall favorite build for Vex, the Blood Shot endgame build here which uses 0 bugs!

Leveling Build

Strengths And Weaknesses

Literal infinite damage
Can use any gun
Very Fun

Infinite Bleed is technically a bug, if you want a non-bugged build click here

Build Variants

Specter

Incarnate - Shotgun

Incarnate - SMG

Specter Variation is my preferred version of the build currently

Skill Tree

Specter

Incarnate - Shotgun

Incarnate - SMG

Points Spent 0 / 49

LMB Allocate

RMB Unallocate

2/5

3/3

5/5

1/1

5/5

3/5

Last 9ish points are entirely up to personal preference, I recommend choosing from the following:

Idle Hands feels very good if you're using a Jakobs shotty with 1 round in the mag
Leeching Attunement is good for the same reason & efense
Guns and Needles is very good if you have a repkit with Action Skill Cooldown Rate or you are abusing 200% amp
Hasty Fiends is great for both movement speed and defense which feels nice Fiendish Invigoration is sick for movement speed
Recurrence is strong damage but it's hard to maintain the stacks unless you use a fast firing weapon or a shotgun with multiple pellets
Grave Assault is good for beefing up the minion damage, or if you are using a full auto weapon
Grave Quickening feels really good for keeping your specters up
Conjunction is decent if you have a good shield, otherwise gun damage uptime is low

Other options:
Cold Iron is weak because we already have hundreds of % of gun damage through our tree + spec tree, so 15% extra gun damage would barely be a 3-5% dmg increase with a 5pt investment, i'd rather take the survivability
Enchantment doesn't work with Dead Ringer

Equipment

Specter

Incarnate - Shotgun

Incarnate - SMG

Weapons

Repkits & Ordnance

Utilities

Gear to look out for

Penetrator Augment which comes on Throwing Knives is EXTREMELY powerful, and enables Bloodletter to stack on itself

Guns: Due to the kinetic synergies, almost any kinetic gun should work well. Ideally a high base damage Jakobs shotgun. Shotguns pair very well with Penetrator Augment + Bloodletter and are overall very strong weapons. Vladof SMGs especially the 'boory' type with a Jakobs ricochet barrel are very strong as well.

The Hot Slugger is my personal favorite gun, check out the written guide here:

Underbarrel Attachments: Spread Launcher, Knife Launcher, and Shotgun. These have internal cooldowns, you can bypass the cooldown by swapping to a different gun with the same attachment.

Repkits: 200% Amp damage (good for shotguns or snipers) 100% action skill cooldown rate

Class mod: Look for points in Bloodletter Material Components or Grave Implements, good stats include: Gun Damage, Shotgun/SMG Damage, Kinetic Damage, Status Damage, Movement Speed, Damage Reduction, Damage Dealt.

Enhancements: Jakobs 2x ricochet or stacking damage buff is good if using Hot Slugger, or use any Vladof enhancement if using a purple smg. Stats that are good: Crit damage, Gun damage, Gun specific crit damage, SMG fire rate, SMG mag size.