Potions are the ultimate life savers in Slay the Spire 2. A one time burst of power can be the difference between survival and getting sucked into the maw of an Insatiable sand worm. Here's how we're ranking them:
Please note this list will not include event potions. All Potions are listed in alphabetical order in their Tiers.
Ranking
S-Tier: The best of the best. These Potions are highly sought after regardless of the situation you're in, and are worth holding on to for boss fights.
A-Tier: Potions in this tier are very powerful, but not quite as broken as those in S tier.
B-Tier: Very solid options but are either not as good, more niche or have a chance to whiff
C-Tier: Your standard helpful Potion that you'll be happy to see but probably stay on the Shopkeeper's rug.
D-Tier: Better than nothing but make you wish you had something else.