Discover all Path of Exile 2 Runes - the bonus each rune grants and the item types it can be socketed into. Runes go into the sockets on weapons and armour, and give a different bonus depending on the item.
PoE 2 Runes

Adept Rune
Requires: Level 31
- All: +9 to Dexterity

Aldur's Legacy
Requires: Level 65
- All: When socketed into a Unique Kalguuran or Ezomyte item, destroys the item to create a Rune imbued with that item's power

Ancient Rune of Animosity
Requires: Level 12
- Talisman: Gain 2 Druidic Prowess when you Heavy Stun a Rare or Unique Enemy

Ancient Rune of Control
Requires: Level 12
- Quarterstaff: 50% increased Immobilisation buildup

Ancient Rune of Decay
Requires: Level 12
- Wand: 25% increased Withered Magnitude

Ancient Rune of Detonation
Requires: Level 12
- Crossbow: Grenades have 10% chance to activate a second time

Ancient Rune of Discovery
Requires: Level 12
- Staff: 30% chance to create an additional Remnant

Ancient Rune of Dueling
Requires: Level 12
- Buckler: 30% increased Parried Debuff Magnitude

Ancient Rune of Prowess
Requires: Level 12
- Spear: 30% chance when you gain a Charge to gain an additional Charge

Ancient Rune of Retaliation
Requires: Level 12
- Shield: 8% increased Attack Speed if you have Blocked Recently

Ancient Rune of Shattering
Requires: Level 12
- One Hand Mace: 40% increased effect of Fully Broken Armour

Ancient Rune of Splinters
Requires: Level 12
- Bow: +50% Surpassing chance to fire an additional Arrow

Ancient Rune of the Horde
Requires: Level 12
- Sceptre: Minions have 8% increased Attack and Cast Speed

Ancient Rune of the Titan
Requires: Level 12
- Two Hand Mace: 10% chance for Slam Skills you use yourself to cause an additional Aftershock

Ancient Rune of Witchcraft
Requires: Level 12
- Focus: 40% increased Area of Effect of Curses

Astrid's Creativity
Requires: Level 65
- All: Can have 1 additional Crafted Modifier

Betrayal of Aldur
Requires: Level 65
- Martial Or Caster Weapon: Transforms all Fire, Cold and Lightning modifiers on the item into equivalent Chaos modifiers

Body Rune
Requires: Level 37
- Martial Weapon: Leeches 4% of Physical Damage as Life
- Wand or Staff: +40 to maximum Energy Shield
- Armour: +45 to maximum Life

Breath of Aldur
Requires: Level 65
- Martial Or Caster Weapon: When socketed, transforms all Fire and Lightning modifiers to equivalent Cold modifiers

Cadigan's Epiphany
Requires: Level 65
- Gloves: Destroys all Augment Sockets on the item to create a Jewel Socket

Carved Cunning
Requires: Level 65
- Helmet: Enemies which are on Full Life cannot Evade your Hits
- Body Armour: Prevent +5% of Damage from Deflected Hits if you've Deflected no Hits Recently
- Boots: Gain Onslaught for 4 seconds when your Marks Activate

Carved Majesty
Requires: Level 65
- Body Armour: +3 to Spirit per Idol socketed in your Equipment
- Gloves: Companions gain Onslaught for 4 seconds on Hitting your Marked targets
- Boots: 1% increased Movement Speed while Sprinting per Persistent Minion

Carved Mischief
Requires: Level 65
- Helmet: Gain Guard equal to 10% of maximum Life for 4 seconds on taking Savage Hit
- Gloves: +5% to maximum Block chance if you've Blocked with a raised Shield Recently
- Body Armour: 200% increased Stun Threshold if you've been Stunned Recently

Carved Tenacity
Requires: Level 65
- Helmet: Enemies have no Critical Damage Bonus for 4 seconds after you Blind them
- Gloves: Enemies you Critically Hit get 100% reduced Life Regeneration Rate for 4 seconds
- Boots: Your speed is Unaffected by Slows while Sprinting

Charging Rune
Requires: Level 31
- Armour: 12% increased Runic Ward Regeneration Rate

Countess Seske's Rune of Archery
Requires: Level 65
- Bow: Bow Attacks fire an additional Arrow

Courtesan Mannan's Rune of Cruelty
Requires: Level 65
- Gloves: 20% increased Magnitude of Damaging Ailments you inflict

Craiceann's Rune of Recovery
Requires: Level 65
- Body Armour: 30% increased Energy Shield Recharge Rate

Craiceann's Rune of Warding
Requires: Level 65
- Body Armour: 50% reduced effect of Curses on you

Desert Rune
Requires: Level 31
- Martial Weapon: Adds 7 to 11 Fire Damage
- Wand or Staff: Gain 8% of Damage as Extra Fire Damage
- Armour: +14% to Fire Resistance

Emergent Instinct
Requires: Level 65
- Helmet: Targets that are Blinded, Maimed, and Bleeding cannot Evade your Hits
- Gloves: Regenerate 5% of maximum Life per Second if you have used a Command Skill Recently
- Body Armour: Thorns Damage is Lucky against targets with Fully Broken Armour

Emergent Possibility
Requires: Level 65
- Body Armour: 15% of Chaos Damage from Hits taken as Damage of a random Element
- Gloves: Gain 1% of Damage as Extra Damage of a random Element per Rune Socketed in Equipped Items
- Boots: 50% increased Runic Ward Regeneration Rate while Sprinting

Emergent Protection
Requires: Level 65
- Helmet: Gain 1 Endurance Charge on reaching Low Life, only once every 2 seconds
- Gloves: Banners also grant 2% of Life Regenerated per second to affected targets
- Boots: When you stop Sprinting, gain Guard equal to 4% of maximum Life per second spent Sprinting, up to a maximum of 20%, for 4 seconds

Emergent Vigour
Requires: Level 65
- Helmet: +1 to maximum Life per 8 Armour on Equipped Helmet
- Body Armour: Gain Maximum Energy Shield equal to 50% of total Strength Requirements of Equipped Armour Items
- Boots: Hits against you have no Critical Damage Bonus while on Consecrated Ground

Farrul's Rune of Grace
Requires: Level 65
- Boots: 8% increased Deflection Rating while moving

Farrul's Rune of the Chase
Requires: Level 65
- Boots: 5% increased Movement Speed

Farrul's Rune of the Hunt
Requires: Level 65
- Martial Weapon: 50% increased Attack Damage against Rare or Unique Enemies

Fenumus' Rune of Agony
Requires: Level 65
- Martial Weapon: Gain 13% of Damage as Extra Chaos Damage
- Wand or Staff: Gain 13% of Damage as Extra Chaos Damage

Fenumus' Rune of Draining
Requires: Level 65
- Gloves: 20% increased Withered Magnitude

Fenumus' Rune of Spinning
Requires: Level 65
- Gloves: 8% increased Cast Speed

Glacial Rune
Requires: Level 31
- Martial Weapon: Adds 6 to 10 Cold Damage
- Wand or Staff: Gain 8% of Damage as Extra Cold Damage
- Armour: +14% to Cold Resistance

Greater Adept Rune
Requires: Level 52
- All: +12 to Dexterity

Greater Body Rune
Requires: Level 57
- Martial Weapon: Leeches 5% of Physical Damage as Life
- Wand or Staff: +50 to maximum Energy Shield
- Armour: +60 to maximum Life

Greater Charging Rune
Requires: Level 52
- Armour: 16% increased Runic Ward Regeneration Rate

Greater Desert Rune
Requires: Level 52
- Martial Weapon: Adds 13 to 16 Fire Damage
- Wand or Staff: Gain 10% of Damage as Extra Fire Damage
- Armour: +18% to Fire Resistance

Greater Glacial Rune
Requires: Level 52
- Martial Weapon: Adds 9 to 15 Cold Damage
- Wand or Staff: Gain 10% of Damage as Extra Cold Damage
- Armour: +18% to Cold Resistance

Greater Inspiration Rune
Requires: Level 62
- Martial Weapon: Gain 30 Mana per enemy killed
- Wand or Staff: 30% increased Mana Regeneration Rate
- Armour: 30% increased Mana Regeneration Rate

Greater Iron Rune
Requires: Level 52
- Martial Weapon: 18% increased Physical Damage
- Wand or Staff: 30% increased Spell Damage
- Armour: 18% increased Armour, Evasion and Energy Shield