VayneAbility Order
- First three = Q - > E -> W
- Then, prioritize maxing:
- Q
Tumble -> W 
Silver Bolts -> E 
Condemn
- Q
Summoner Spells
Flash + 
Barrier
Use your favourite features in-game with our Desktop AppAbility Order + Summoner Spells
Items
Starter Items
Full Build
Runes
- Marks
Greater Mark of Attack Damage x9
- Seals
Greater Seal of Armor x9
- Glyphs
Greater Glyph of Magic Resist x9
- Quintessences
Greater Quintessence of Life Steal x3
The best Runes for Vayne are 9x Mark of Attack Damage, 9x Seal of Armor, 9x Glyph of Magic Resist, and 3x Quintessence of Life Steal. The AD and Life Steal will help Vayne with trading, and the Armor will help to block incoming autos, as Vayne is quite squishy and vulnerable. Magic Resist will help vs AP champs.
Masteries
As Vayne is an ADC, she will go 21 points in the offensive tree and 9 in the defensive tree. The defensive tree is a must as Vayne is quite squishy, and the extra stats are going to help protect her against strong all-in champions. The 21 points into offence are standard ADC Masteries, which will help last hit minions and while trading.
Changes For Classic
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Table of Contents
Overview
Our experts are currently testing LoL Classic builds for 
Vayne on the PBE.
Check back often as we make updates based on PBE changes and as the Classic meta develops!
How to Play
Vayne excels in the mid and late game and is a strong carry, but she is very vulnerable and weak early on. Focus on farming and gaining XP, while maintaining distance from the enemy ADC and Support, so you don’t get collapsed on. Save your Q and E to protect you from all-ins.
During the mid-game, your goal is to move around the map with your Support and try to take objectives. Look to team fight after you have a few items completed, as you’re strong in team fights when you have multiple items.
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