Knock an enemy back into your team by using R and quickly Flashing behind them. E to gap close, then Q and AA three times before using W and AAing again.
To isolate a target E onto them, AA then use R and AA again.
For your standard full combo E to your target, then AA and use Q. AA some more before using W, then AA R AA.
When already in melee range, AA then Q and AA some more. Use E to follow your target, then AA W AA.
You can extend your W range by quickly Flashing after casting.
For max damage on objectives use E followed by AA W AA. Q and then AA some more.
To trade pre-6 E onto your target, then Q. AA three times, then W and AA again.