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Cassiopeia·Runes for Mid

Win rate	53.8%
Pick rate	2.7%
Ban rate	7.3%
Matches	14 349-

Cassiopeia Mid has a 53.8% win rate with 2.7% pick rate in Emerald + and is currently ranked S tier. Based on our analysis of 14 349 matches in Patch 15.1 the best runes for Cassiopeia Mid are keyStone, rune_1, rune_2, and rune_3 for primary tree, as well as secondary_rune_1 and secondary_rune_2 for secondary tree. The most optimal rune shards are offenseRuneShard, flexRuneShard, and defenceRuneShard.

Builds

ARAM

Arena

Counters

Guide

Combos

Builds

Runes

Expert Video Guide

Cassiopeia Runes

Mid ∙ Patch 15.1

Keystone options

Keystone

Cassiopeia Matchups Overview

Cassiopeia General information

Cassiopeia tips and tricks

In the early game, always keep an eye on your mana pool when trading as it goes quicker than you expect when trading with the enemy.

Only commit to a trade with the enemy when you’ve successfully landed a Noxious Blast Q. You can follow the initial Q with multiple Twin Fang E’s afterwards for a favourable trade.

Cassiopeia has strong all-in potential at level 2 with her Noxious Blast Q and Twin Fang E spam. If you’re in a strong matchup and against a squishy champion, you should try to get an early lead once you get the level up.