The viability of each Potion varies greatly depending on its tier and enchantments. Pretty much any Potion can be used under the right circumstances, so even those not mentioned here can still be worth including.
At the end of the day, unless you're purely going for speed (ex.
Recycling Bin +
Vial Launcher), it's going to come down to whatever you roll throughout your several Transforms. Don't worry, with enough time, you're likely to roll something spicy!
Core Synergies
Recycling Bin is incredibly strong as it provides fantastic Cooldown Reduction while solving Ammo. It's a lead indicator for a Potion build, worthy of a pivot.- It's almost always worth picking up in case you find
Vial Launcher later on, since filling up with Potions is flexible and easy.
Runic Potion is the third piece of the combo which grants Lifesteal to
Vial Launcher.
Boiling Flask is another excellent choice for its Multicast support. While it does Reload, having 1-2 extra Ammo is useful due to its long Cooldown.
Potion Distillery can be a great source of Ammo and Cooldown Reduction. While it's a staple in the stash, it's definitely worth considering for the board.
Show Globe is a good early to mid game win condition before better alternatives are found. With a board full of Potions, the Burn/Regen scales pretty well.
Energy Potion provides excellent board-wide Haste support, particularly after upgrades, or with a Turbo enchant.
Frost Potion,
Strength Potion, and
Invulnerability Potion all provide situational but useful utility (
Frost Potion at Gold+ for extra targets).
Tips & Tricks
- Ammo is a very relevant aspect of Potion builds. Acquiring
Stocked and/or
Gunner can greatly impact what's required on board. - With enough additional board-wide Ammo, you can often get away with little to no Reload support.
- Most of the key win conditions exist at Gold. Ideally you'll find one early, but if not, you can keep Transforming Gold Reagents/Potions to look for options.
- Obsidian/Fiery/Toxic
Vitality Potion is ridiculously strong.
Alembic,
Cellar, and
Sifting Pan are additional
Catalyst spawners if you need them.